PHOD — Candida albicans

Summary

C1_11480W_A (PHOD, also known as PHO84) in Candida albicans encodes a protein belonging to the major facilitator superfamily (MFS) of sugar transport-like proteins, with a Phos_permease domain. The gene product is annotated with high-affinity phosphate transmembrane transporter activity, glycerol-3-phosphate transmembrane transporter activity, glycerophosphodiester transmembrane transporter activity, selenite:H+ symporter activity, phosphate ion binding, manganese ion transmembrane transporter activity, phosphate transmembrane transporter activity, carboxylic acid transmembrane transporter activity, and transmembrane transporter activity. PHOD is associated with Pi homeostasis, glycan biosynthesis, glycerophosphodiester transmembrane transport, carboxylic acid transport, plasma membrane selenite transport, down-regulation by symbiont of host gene-for-gene resistance, metabolic burst, phosphate ion membrane transport, phosphate ion transport, intracellular Pi homeostasis, polyphosphate metabolism, TOR signaling, TORC1 signaling, cellular response to oxidative stress, hyphal growth, detoxification, ergosterol anabolism, and morphogenesis. It localizes to the cell periphery, vacuolar membrane, fungal-type vacuole, Golgi membrane, ER membrane, and plasmalemma. The gene is associated with biofilm formation, spore germination, protein/peptide accumulation, fermentative growth, cell cycle progression, vacuolar distribution, desiccation resistance, freeze-thaw resistance, aneuploidy, mitophagy, and respiratory metabolism. Related genes in other species