LIP1 — Candida albicans

Summary

C1_09580C_A (LIP1, also known as CaTRI8 or TRI8) on chromosome 1 of Candida albicans encodes a secreted lipase belonging to the AB hydrolase family, with lipase activity (EC 3.1.1.3) and triacylglycerol lipase activity. This gene is associated with lipolysis, biofilm formation, filamentous growth in response to starvation and biotic stimuli, cellular response to starvation, secretion, cell growth, and release of cytochrome c from mitochondria. The encoded protein is localised extracellularly. Related genes in other species, including Fusarium oxysporum, are linked to secreted lipase function, though these associations are not established for LIP1 itself.