ATRR — Aspergillus nidulans FGSC A4

Summary

ANIA_04558 (ATRR, AnATRR) encodes a Zn2Cys6 DNA-binding transcription factor of the AtrR-like family, with sequence-specific DNA binding and RNA polymerase II transcription factor activity. In Aspergillus nidulans, ATRR is associated with positive regulation of transcription, ergosterol anabolism, biofilm formation, and hypersensitivity. The gene product localises to the nucleus, chromatin, cytosol, and membrane. Studies of related genes in other species link the ATRR family to reduced virulence and pulmonary aspergillosis, as well as to plant pathogens including Verticillium dahliae and Fusarium oxysporum.