nhmT — Aspergillus nidulans FGSC A4

Summary

ANIA_04663, symbol nhmT, on Aspergillus nidulans FGSC A4 chromosome 3, encodes a protein with a SAM-dependent methyltransferase superfamily domain and exhibits peptidyl-histidine N-methyltransferase activity (EC 2.1.1.85) as well as protein lysine methylase activity. The gene is associated with post-translational modification and methylation processes, and its product localises to the endoplasmic reticulum membrane. Studies of related genes in other species link the nhmT family to these methylation functions, though such roles are not yet established in A. nidulans.