prnB — Aspergillus nidulans FGSC A4

Summary

ANIA_03876 (prnB) on chromosome 2 of Aspergillus nidulans FGSC A4 encodes an amino acid permease belonging to the APC_YAT and AA-permease/SLC12A_dom families, with molecular functions including L-proline, L-histidine, L-arginine, and L-lysine transmembrane transporter activity, as well as basic amino acid permease activity. The gene is associated with proline transport, import, metabolism, and breakdown, response to proline and amino acid starvation, carbon catabolite repression, regulation of nitrogen utilization, and basic amino acid transport. It is linked to localization at the eisosome, fungal-type cell wall, Golgi membrane, cell tip, ER, and plasmalemma. Related genes in other species are associated with reduced virulence.