AMD2 — Aspergillus nidulans FGSC A4

Summary

The Aspergillus nidulans gene AnAMD2 (also known as GMDA, FAH1, AnFAH1, or AnGMDA) on chromosome 2 encodes a protein with amidase and fatty acid amide hydrolase activity (EC 3.5.1.4), belonging to the amidase domain family. This gene is associated with carbon catabolite repression, catabolite repression, antibiotic anabolism, and fatty acid breakdown. Its product has been localized to the cytoplasm, cytosol, and nucleus. Studies of related genes in other species link the family to altered competitive fitness, starvation resistance, and chemical resistance phenotypes, as well as to interactions with plant pathogens such as Verticillium dahliae and Fusarium oxysporum pathovars.