nimX — Aspergillus nidulans FGSC A4

Summary

ANIA_04182 (nimX) on chromosome 2 of Aspergillus nidulans FGSC A4 encodes a cyclin-dependent protein kinase (CDK) with serine/threonine kinase activity, ATP binding, cyclin binding, and histone binding, classified as EC 2.7.11.22. The gene is associated with the regulation of mitotic and meiotic cell cycle processes, including DNA replication, spindle elongation, chromosome attachment, telomere tethering, and phase transitions, as well as responses to DNA damage and integrity checkpoint signaling. It is linked to the positive regulation of protein breakdown, glycogenolysis, and triglyceride catabolism, and to the regulation of glucose starvation responses, primary cell septum biogenesis, and budding cell apical bud growth. The product localizes to CDK holoenzyme complexes, spindle pole bodies, meiotic and mitotic spindles, telomeric chromosome regions, and ascospore-type prospores.