AMDR — Aspergillus nidulans FGSC A4

Summary

The gene ANIA_04035, symbol AMDR (amdR) in Aspergillus nidulans FGSC A4 on chromosome 2, encodes a Zn2Cys6 DNA-binding transcription factor with RNA polymerase II-specific activity. It belongs to the amide-lactam regulator family and localises to the nucleus. The gene is associated with carbon catabolite repression, catabolite repression, and positive regulation of transcription by RNA polymerase II. It has been linked to penicillin anabolism, fatty acid breakdown, and DNA-mediated transformation. Studies of related genes in other species connect the family to similar regulatory roles.