amdS — Aspergillus nidulans FGSC A4

Summary

ANIA_00783 (amdS) on chromosome 8 of Aspergillus nidulans encodes a general amidase with amidase, fatty acid amide hydrolase, and glutaminyl-tRNA synthase (glutamine-hydrolyzing) activities, and it contains an amidase domain. The gene is associated with DNA-mediated transformation, DNA integration, regeneration, karyogamy, carbon catabolite repression, acetate metabolism, the glyoxylate cycle, penicillin and antibiotic anabolism, osmotic response, mitotic recombination, regulation of gene expression, translation termination and initiation, and glutaminyl-tRNAGln biosynthesis via transamidation. It is linked to the glutamyl-tRNA(Gln) amidotransferase complex and localises to mitochondria, cytoplasm, cytosol, and nucleus. Related genes in other species connect the family to EC 3.5.1.4 (amidase) and EC 6.3.5.7 (glutaminyl-tRNA synthase).