MAD1 — Aspergillus nidulans FGSC A4

Summary

ANIA_00696 (MAD1) on chromosome 8 of Aspergillus nidulans FGSC A4 encodes the spindle assembly checkpoint component MAD1, a kinetochore adaptor. The gene is associated with activation of the mitotic cell cycle spindle assembly checkpoint, negative regulation of protein import into the nucleus during the spindle assembly checkpoint, plus-end directed chromosome gliding, the mitotic DNA integrity checkpoint, attachment of spindle microtubules to mitotic chromosomes, and the spindle checkpoint. It is linked to prophase, anaphase, interphase, mitosis, chromosome division, cell division, nucleocytoplasmic transport, and nuclear import. The encoded protein localises to the kinetochore, mitotic spindle, mitotic spindle pole body, nuclear envelope, nucleoplasm, and NPC.