ABAA — Aspergillus nidulans FGSC A4

Summary

ANIA_00422 (ABAA, abaA) in Aspergillus nidulans FGSC A4 encodes a protein with a TEA/ATTS domain and is a DNA-binding transcription activator with sequence-specific DNA binding activity. The gene is associated with positive regulation of phialide development, conidium formation, and asexual sporulation, as well as cleistothecium formation, mating behavior, conidiophore development, pigmentation, autolysis, and mannitol and chitin anabolism. It localizes to the nucleus, chromatin, and transcription regulator complex. Studies of related genes in other species link the TEA/ATTS family to virulence phenotypes, including hypervirulence and loss of pathogenicity, though these associations are not established for A. nidulans.