gprK — Aspergillus fumigatus

Summary

AFU4G01350 (symbol gprK) on Aspergillus fumigatus chromosome 4 encodes an RGS domain-containing protein with GTPase-activating protein (GAP) activity. This product is associated with negative regulation of GPCR protein signaling pathways and signal transduction, and localizes to the internal side of the plasma membrane. The gene has also been associated with oxidative stress response. Related genes in other species, including Fusarium and Verticillium species, also encode RGS domain-containing proteins.