malA — Aspergillus fumigatus

Summary

AFU4G01460 (malA) in Aspergillus fumigatus encodes a flavin-dependent halogenase, a protein containing a flavin halogenase domain and a FAD/NAD-binding superfamily domain, and is also associated with monooxygenase activity. The gene is linked to secondary metabolite biosynthesis and has been connected to immune-related processes including humoral immune response, sensitization, hypersensitivity, and immune response. Studies of related genes in other species associate the family with FAD-binding and oxidoreductase activity (EC 1.14.14.-).