mp1 — Aspergillus fumigatus

Summary

AFU4G03240 (mp1) in Aspergillus fumigatus encodes a cell wall mannoprotein 1, a structural constituent of the cell wall with fatty acid and lipid binding properties. This gene is associated with mannan anabolism, protein secretion, fungal-type cell wall organization, morphogenesis, and autophagy. The encoded product localizes to the yeast-form cell wall, hyphal cell wall, and extracellular space. Studies of related genes in other species link the family to cytoplasmic effector functions, though this has not been established for A. fumigatus.