eng2 — Aspergillus fumigatus

Summary

AFU2G14360 (symbol eng2, also known as AfGH16-1 or GH16-1) on chromosome 2 of Aspergillus fumigatus encodes a mixed-linked glucanase belonging to the glycosyl hydrolase 16 (GH16) family. The enzyme possesses lichenase and endo-1,3(4)-beta-glucanase activity (EC 3.2.1.6). The gene is associated with fungal-type cell wall polysaccharide metabolism, autolysis, cell wall assembly, glucan and cellulose breakdown, hyphal growth, and morphogenesis. The encoded protein localises to the fungal-type cell wall, the side of the membrane, the plasma membrane, and the extracellular space. eng2 has also been linked to germination rate. Studies of related genes in other species have connected the family to apoplastic effector functions.