fluG — Aspergillus fumigatus

Summary

AFU2G15390 (fluG) on Aspergillus fumigatus chromosome 2 encodes a protein with glutamine synthetase and hydrolase activities, containing a glutamine synthetase catalytic domain. The gene is associated with asexual reproduction, including positive regulation of conidium formation and sporocarp development involved in asexual reproduction. It has been connected to the regulation of sterigmatocystin and aflatoxin biosynthetic processes, secondary metabolism, sterol metabolism, autolysis, and hyphal growth. The product localizes to the cytoplasm. Studies of related genes in other species link the fluG family to oxidative stress response.