YA — Aspergillus fumigatus

Summary

AFU2G17530 (symbol YA, also known as abr2) in Aspergillus fumigatus encodes a multicopper oxidase of the cupredoxin family, with p-diphenol:oxygen oxidoreductase activity and copper-binding and redox functions. The gene is associated with L-phenylalanine breakdown, pigmentation, melanin and (M)-viriditoxin anabolism, conidiophore development, sporulation, sexual reproduction, mating, homologous recombination, and homeostasis. Its product is localised to the membrane, cell-bound, and extracellular compartments. Studies of related genes in other species link the family to laccase activity (EC 1.10.3.18) and to fusarium head blight and ear blight, though pathogenicity is unaffected in those contexts.