FLBB — Aspergillus fumigatus
Summary
AFU2G14680 (FLBB, flbB) in Aspergillus fumigatus encodes the bZIP transcription factor FlbB, a DNA-binding transcriptional activator that binds cis-regulatory regions and acts via RNA polymerase II. This gene is associated with conidiophore development, sporulation, autolysis, cell death, cell wall organization, and secondary metabolism. The encoded protein localizes to the RNA polymerase II transcription regulator complex. Studies of related genes in other species link the family to oxidative stress response.
Annotations
- Chromosome
- 2
- Related genes
- FLBB
- GO terms
- Cell Death, Sporulation, Cell Wall Organization, DNA-binding Transcription Activator Activity, RNA Polymerase II-specific, Transcription Cis-regulatory Region Binding, RNA Polymerase II Transcription Regulator Complex, secondary metabolism, Autolysis
- Publications
- PMID:19729403, PMID:25014896, PMID:19656299, PMID:19007409, PMID:16387865, PMID:17993569, PMID:31779253, PMID:9073485
- Traits
- oxidative stress response