TPT1 — Aspergillus fumigatus

Summary

AFU2G02890 (symbol TPT1, preferred name AfTPT1) in Aspergillus fumigatus chromosome 2 encodes a tRNA 2′-phosphotransferase (EC 2.7.1.160). The protein contains RNA 2′-phosphotransferase domains (RNA_2′-PTrans_C, RNA_2′-PTrans_N, and Ptrans_KptA/Tpt1) and is annotated to the biological process of tRNA splicing via endonucleolytic cleavage and ligation. It is localised to the nucleus. The gene is associated with the TPT1 family, and studies of related genes in other species link the family to essential cellular functions. No direct associations with agronomic traits have been observed in this species.