FLBD — Aspergillus fumigatus

Summary

AFU1G03210 (symbol FLBD, also known as flbD) on chromosome 1 of Aspergillus fumigatus encodes a MYB family conidiophore development protein, FlbD, which has RNA polymerase II cis-regulatory region sequence-specific DNA binding and DNA-binding transcription factor activity, RNA polymerase II-specific. The protein localises to the nucleus and is associated with conidiophore development, asexual reproduction, sporulation, hyphal growth, biofilm formation, and autolysis. It is linked to regulation of the cell cycle G1/S phase transition, mitotic cell cycle, regulation of DNA re-duplication, carbon catabolite repression, secondary metabolism, sterol metabolism, and response to lipid, activation of salinity response, and upregulation of response to thirst. Additional associations include regulation of stomatal complex patterning and multicellular organismal water homeostasis. Related genes in other species link the family to germination rate and oxidative stress response.