ABAA — Aspergillus fumigatus

Summary

AFU1G04830 (symbol ABAA, also known as abaA) encodes a TEA/ATTS domain-containing transcription factor with DNA-binding transcription activator activity, localised to the nucleus and chromatin. In Aspergillus fumigatus, this gene is associated with the positive regulation of phialide development, conidiophore development, asexual sporulation, conidium formation, and germ tube formation. It is also linked to mating behaviour, autolysis, carbon catabolite repression, pigmentation, biofilm formation, and tube formation. Studies of related genes in other species connect the family to sporogenesis and altered virulence, including hypervirulence and loss of pathogenicity.