prtT — Aspergillus fumigatus

Summary

AFU1G06540 (prtT) on Aspergillus fumigatus chromosome 1 encodes a putative C6 transcription factor, a Zn2Cys6 DNA-binding domain protein. It is annotated with transcription cis-regulatory region binding, DNA-binding transcription factor activity, and zinc binding, and localises to the nucleus. The gene is associated with regulation of DNA-templated transcription, oligopeptide transport, proteolysis, protein breakdown, secretion, ergosterol anabolism, cell death, and DNA-dependent transcription. Studies of related genes in other species link the prtT family to similar C6 zinc finger transcription factor functions, though these associations are not established for A. fumigatus itself.