mfsB — Aspergillus fumigatus

Summary

AFU1G03730 (symbol mfsB) on Aspergillus fumigatus chromosome 1 encodes a transmembrane transporter belonging to the major facilitator superfamily (MFS). The gene is associated with pigmentation, hyphal growth, and homeostasis, and its product localises to the plasma membrane and membrane. Studies of related genes in other species link the MFS family to cytoplasmic and apoplastic effector functions, as well as to traits such as germination rate, oxidative stress response, and phosphorus concentration. The gene is also connected to several fungal pathogens, including Verticillium dahliae and Fusarium oxysporum strains, through sequence similarity.