HOG1 — Verticillium dahliae

Summary

VDAG_08982, designated VdHOG1 in Verticillium dahliae (chromosome DS572718), encodes a mitogen-activated protein kinase of the MAPK_Sty1/Hog1 family with serine/threonine kinase activity (EC 2.7.11.24). The gene is associated with the stress-activated MAPK cascade, the high-osmolarity glycerol (HOG) response, osmolarity sensing, and cellular responses to heat and oxidative stress. It is linked to conidium development, melanin anabolism, calcium signaling, protein kinase A activation, signal transduction, and DNA-dependent transcription. The encoded protein localises to both the cytoplasm and nucleus. VdHOG1 is connected to vascular wilt disease in V. dahliae and has been associated with traits including osmotic stress resistance, cell cycle progression, mating efficiency, and nutrient uptake. Studies of related genes in other species link the family to virulence, turgor pressure, and germination rate.