FREB — Verticillium dahliae

Summary

VDAG_09220 (FREB) in Verticillium dahliae encodes a ferric-chelate reductase (NADPH) (EC 1.16.1.9), a member of the ferric/cupric reductase family with FAD- and NAD-binding domains. The enzyme is associated with cellular iron ion homeostasis, iron transport, and copper ion import, and localises to the plasmalemma. Studies of related genes in other species link the family to reduced virulence and vascular wilt disease, though these phenotypes are not established for this gene. The gene is also associated with metal binding.