PEL1 — Verticillium dahliae
Summary
VDAG_09271 (VdPEL1) in Verticillium dahliae encodes a CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase (EC 2.7.8.5), a member of the PLipase_D/transphosphatidylase family also known as PGS1. This mitochondrial membrane protein is associated with cardiolipin biosynthesis and CDP-diacylglycerol anabolism. The gene is linked to numerous phenotypes including decreased colony size, abnormal mitochondrial morphology, increased hyperosmotic stress resistance, decreased osmotic and ionic stress resistance, increased cold sensitivity, decreased UV resistance, and abnormal cellular morphology. It is also connected to increased apoptosis rate, decreased mitochondrial transport, and altered carbon source utilization.
Annotations
- Chromosome
- DS572719
- Related genes
- PEL1, PGS1, PET9, UPS1, TAM41, KRE5, CHO1
- GO terms
- Cell Death, Cardiolipin Biosynthetic Process, ATP Binding, CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase Activity, mitochondrial lumen, mitochondria, CDP-diacylglycerol anabolism, Mitochondrial Membrane Organization
- Publications
- 22447934, 28673963, 28167678, 28369054, 34713605, 19401462, 18408719, 23062277
- Traits
- RESISTANCE TO CHEMICALS: DECREASED, COMPETITIVE FITNESS: DECREASED, INVIABLE, RESISTANCE TO CHEMICALS: INCREASED, RESPIRATORY GROWTH: DECREASED, RNA ACCUMULATION: INCREASED, CHROMOSOME/PLASMID MAINTENANCE: ABNORMAL, VEGETATIVE GROWTH: DECREASED