freB — Verticillium dahliae

Summary

VDAG_09283 (freB) on chromosome DS572719 of Verticillium dahliae encodes a ferric reductase transmembrane component 6, a member of the Ferric/Cupric_Reductase family with FAD-binding and NADH:Fe3+ oxidoreductase activity. The gene is associated with iron chelate reductase and ferric-chelate reductase (NADPH) activity, metal binding, and localises to the plasmalemma. It is associated with cellular response to iron ion starvation, iron transport and homeostasis, copper ion import, and filamentous growth. Related genes in other species link the family to reduced virulence and vascular wilt, though these associations are not yet established for V. dahliae freB itself.