GIT7 — Verticillium dahliae
Summary
VDAG_09361 (VdGIT7, also known as VdSGT1) on chromosome DS572719 of Verticillium dahliae encodes an SGT1 protein containing SGS, CS and HSP20-like chaperone domains, and is annotated with chaperone protein binding activity. The gene is associated with the glucose-sensing PKA pathway, protein folding, secretion, and cell death, and its product localises to the cytoplasm, cytosol and nucleus. Associations with numerous phenotypes include increased starvation resistance and respiratory metabolism, altered cell cycle progression (including G1/S arrest and G2/M delay), abnormal chromosome segregation, meiotic recombination, budding, nuclear import and position, decreased mating response and gamma ray resistance, absent pexophagy and mitochondrial genome maintenance, and altered autophagy.
Annotations
- Chromosome
- DS572719
- Related genes
- RP11-93H24.2, GIT7, SGT1, AHA1, CNN1, UBR1, PPT1, PRC1
- GO terms
- Secretion, Cell Death, Protein Folding, Nucleus, Cytoplasm, Cytosol, chaperone protein binding, glucose-sensing PKA pathway
- Publications
- 9491072, 27571477, 27723736, 19299562, 22505624, 34502421, 32376972, 22461145
- Traits
- RESISTANCE TO CHEMICALS: DECREASED, COMPETITIVE FITNESS: DECREASED, STRESS RESISTANCE: DECREASED, INVIABLE, RESISTANCE TO CHEMICALS: INCREASED, CELL CYCLE PROGRESSION: ABNORMAL, NUCLEAR POSITION: ABNORMAL, RESISTANCE TO CHEMICALS: NORMAL