EXO70 — Verticillium dahliae

Summary

VDAG_09051, designated VdEXO70, encodes the exocyst complex protein EXO70. The protein contains an Exo70_C domain and is annotated for phosphatidylinositol-4,5-bisphosphate binding and small GTPase binding. In Verticillium dahliae, VdEXO70 is associated with exocyst assembly and localization, exocytosis, protein secretion, and Golgi-to-plasma membrane transport. It localizes to the exocyst, plasma membrane, and cellular bud sites. The gene is linked to numerous phenotypes including abnormal filamentous growth, budding, septum formation, and spore wall formation; altered thermotolerance, mating efficiency, and pheromone response; and decreased necrotic cell death. VdEXO70 also shows associations with septin ring organization, Rho protein signal transduction, and abnormal endoplasmic reticulum and Golgi distribution.