CAT1 — Verticillium dahliae

Summary

VDAG_09115 (VdCAT1) encodes a catalase enzyme (EC 1.11.1.6) with catalase activity, heme binding, and metal binding functions, belonging to the catalase clade 1/3 family. It is localized to peroxisomes, mitochondria, cytoplasm, and the fungal cell wall. VdCAT1 is associated with hydrogen peroxide metabolic and catabolic processes, cellular detoxification of hydrogen peroxide, response to hydrogen peroxide, metabolic burst, filamentous growth, starvation responses, alkaloid metabolism including fumigaclavine C anabolism, and interaction with host. Phenotypic associations include increased pexophagy, increased entry into G0 phase, increased survival in stationary phase, increased ionic stress resistance, increased meiotic recombination, increased mitochondrial rho- mutation frequency, increased starvation resistance, decreased utilization of sulfur source, decreased fermentative metabolism, decreased mitochondrial transport, decreased anaerobic growth rate, decreased pheromone-induced cell cycle arrest, absent oxidative stress resistance, absent silencing, and sterile mating response.