FREB — Verticillium dahliae

Summary

VDAG_09198 (FREB) in Verticillium dahliae encodes a ferric-chelate reductase (NADPH) with NADH:Fe3+ oxidoreductase activity (EC 1.16.1.9), belonging to the ferric/cupric reductase family and containing FAD- and NAD-binding domains. The protein localises to the plasma membrane and is associated with cellular iron ion homeostasis, iron transport, cellular response to iron ion starvation, copper ion import, and filamentous growth. Related genes in other species are linked to reduced virulence and vascular wilt.

Annotations

Chromosome
DS572717
Related genes
FREB, AFU8G06210, AFU7G07120, ANIA_07981, VDAG_09138
GO terms
metal binding, plasmalemma, Ferric-chelate Reductase (NADPH) Activity, cellular iron ion homeostasis, Copper Ion Import, iron chelate reductase activity, iron transport, Cellular Response To Iron Ion Starvation
Publications
PMID:15790671, PMID:17419877, PMID:15917516, PMID:21840411, PMID:10784045, PMID:12760852, PMID:25130162, PMID:8828219
Traits
reduced virulence