HSP70 — Verticillium dahliae

Summary

VDAG_09146, designated HSP70 in Verticillium dahliae on chromosome DS572717, encodes a heat shock cognate HSP70 protein with ATP hydrolase activity, ATP binding, peptide binding, heat shock protein binding, and protein folding chaperone functions. It belongs to the Hsp_70_fam and HSP70_peptide-bd_sf families. The gene is associated with protein refolding, protein acetylation, translation, protein breakdown, ergosterol anabolism, and cellular responses to heat, farnesol, and osmotic stress. Its product localizes to the cytoplasm, cytosol, hyphal cell wall, plasma membrane, extracellular region, fungal biofilm matrix, and protein aggregate centers. HSP70 is also linked to amino acid content. Studies of related genes in other species connect the family to the enzyme class 3.6.4.10.