CAT2 — Verticillium dahliae

Summary

VDAG_09046 (VdCAT2) on chromosome DS572718 of Verticillium dahliae encodes a protein with carnitine acyltransferase domains and is annotated for carnitine O-acetyltransferase activity (EC 2.3.1.7), fatty acid synthase activity, phosphopantetheine binding, methyltransferase activity, redox activity and zinc binding. The gene is associated with carnitine metabolism, fatty acid metabolism and anabolism, antibiotic anabolism, secondary metabolite biosynthesis, methylation and metabolic burst. Its product localises to the peroxisome and mitochondrial inner membrane. Phenotypic associations link VdCAT2 to increased vegetative growth, increased exponential-phase growth, increased anaerobic growth, increased freeze-thaw resistance, increased starvation resistance, increased lifespan, increased osmotic stress resistance, increased carbon source utilisation, increased pseudohyphal growth, increased respiratory metabolism, and increased Golgi distribution, as well as absent desiccation resistance, absent pseudohyphal growth, decreased invasive growth, decreased mating response, decreased entry into G0, decreased reticulophagy, abnormal cell wall morphology, abnormal nuclear position, abnormal peroxisomal morphology, delayed metaphase-anaphase transition, arrested telophase, and increased cell cycle progression in M phase.