GST1 — Verticillium dahliae

Summary

VdGST1 (VDAG_08979) of Verticillium dahliae encodes a URE2 protein with glutathione transferase, glutathione peroxidase, phosphoprotein binding, and transcription corepressor activities. It contains glutathione S-transferase N-terminal and C-terminal domains. The gene is associated with defense response, cellular detoxification, nitrate assimilation, regulation of nitrogen utilization, protein urmylation, virus-induced PTGS, and negative regulation of RNA polymerase II transcription. It localizes to the cytoplasm, cytosol, and nucleus. Phenotypic associations include abnormal mating type switching, decreased hypoosmotic stress resistance, absent alkaline pH resistance, increased carbon source utilization, increased fermentative growth, decreased adhesion, increased entry into G0 phase, and sterility. Related genes in other species link the family to prion inheritance.