CP1 — Verticillium dahliae

Summary

VdCP1 (VDAG_05135) of Verticillium dahliae encodes a serine carboxypeptidase, a member of the peptidase S10 family with an AB hydrolase domain. The gene is associated with proteolysis, secretion, and methylation, and its product localises to the extracellular space, the plasma membrane, the fungal-type vacuole, and the side of the membrane. VdCP1 has been linked to numerous cellular processes including autophagy, mitophagy, pexophagy, ribophagy, endocytosis, cytokinesis, nuclear fusion during mating, and Golgi morphology. It is also associated with phenotypes such as altered cell death, necrotic cell death, prion inheritance, aneuploidy, protein secretion, replicative lifespan, and entry into stationary phase. Studies of related genes in other species link the family to apoplastic effector functions.