SIB1 — Verticillium dahliae

Summary

VDAG_05314 (VdSIB1) on chromosome DS572704 of Verticillium dahliae encodes a protein with peptide synthase and ligase activity, containing adenylation, condensation, and phosphopantetheine-binding domains. The gene is associated with the biosynthesis of siderophores, including ferrichrome and ferricrocin, as well as melanin and other secondary metabolites. It is linked to cellular responses to iron ion starvation, iron homeostasis, and siderophore-iron import. VdSIB1 has been associated with vascular wilt disease in cotton (Gossypium hirsutum) and Nicotiana benthamiana. The protein localises to the cytoplasm and cytosol. Related genes in other species are linked to pathogenicity traits such as fusarium head blight in wheat and southern corn leaf blight in maize.