MEP1 — Verticillium dahliae

Summary

VDAG_05448, designated MEP1 (VdMEP1) on chromosome DS572704 of Verticillium dahliae, encodes a metallopeptidase belonging to the peptidase M43 family. The enzyme exhibits metallopeptidase activity and metal binding, and is associated with proteolysis and secretion to the extracellular space. The gene is associated with evasion of symbiont recognition by host pattern recognition receptor. Studies of related genes in other species link the MEP1 family to effector functions, including both apoplastic and cytoplasmic effectors, and to reduced virulence.