PREB — Verticillium dahliae

Summary

VDAG_05622, also known as VdPREB, encodes a pheromone receptor with mating-type factor pheromone receptor activity, belonging to the GPCR_STE2 family. In Verticillium dahliae, this gene is associated with mating, chemotropism, and hyphal growth. Phenotypic associations link VdPREB to mating efficiency, cell fusion, shmoo formation, pheromone sensitivity and production, cell cycle progression, endocytosis, vesicle distribution, vacuolar transport, and protein accumulation. The gene is also associated with sterile phenotypes and abnormal mating responses. Studies of related genes in other fungi link the family to oxidative stress response.