UBI — Verticillium dahliae

Summary

VDAG_05595 (VdUBI) encodes a ubiquitin-domain protein that also contains a ribosomal eL40 domain and is annotated with enzyme inhibitor activity, protein tag function, and structural constituent of ribosome. In Verticillium dahliae, this gene is associated with protein ubiquitination, modification-dependent proteolysis, the proteasomal pathway, cellular response to stress and heat, cell wall assembly, protein secretion, cell morphogenesis, filamentous growth, phenotypic switching, and mitotic and meiotic cell cycle modulation. The product localizes to the cytosolic ribosome, cytoplasm, nucleus, and plasmalemma. This gene is associated with abnormal mitophagy, micronucleophagy, premature apoptosis, absent oxidative stress resistance, altered cell cycle progression, decreased colony sectoring, and impaired carbon source utilization and alkaline pH resistance. Related genes in other species are linked to reduced virulence and oxidative stress response.