trx — Verticillium dahliae

Summary

VDAG_02812 (symbol trx) in Verticillium dahliae encodes a thioredoxin-domain protein with protein-disulfide reductase and antioxidant activities, annotated to cell redox homeostasis, cellular detoxification of hydrogen peroxide, and toxic metabolite repair. The gene is associated with defense response, host invasion, and negative regulation of transcription by RNA polymerase II. Its product localises to the cytoplasm, cytosol, nucleus, nuclear periphery, and mitochondria. Associations with related genes txl1 and cox1102 are noted. Related genes in other species link the family broadly to redox regulation and pathogenicity, though these relationships are not yet established for this specific gene.