HH1 — Verticillium dahliae

Summary

VDAG_00818 (VdHH1) in Verticillium dahliae encodes a calcium/calmodulin-dependent protein kinase type I with protein serine/threonine kinase activity, calmodulin binding, and ATP binding. The gene is associated with ethylene anabolism, upregulation of spore germination, and negative regulation of calcineurin-mediated signaling. It has been linked to mitotic and meiotic cell cycle processes including spindle assembly checkpoint, chromosome segregation, and cytokinesis, as well as cellular response to calcium ions. VdHH1 is associated with localisation at kinetochores, spindle midzone, division septum, and the cell cortex. Related genes in other species link the family to cell cycle regulation and calcium signaling pathways.