CP1 — Verticillium dahliae

Summary

VdCP1 (VDAG_00500) in Verticillium dahliae encodes a serine carboxypeptidase (EC 3.4.16.-) with a peptidase S10 domain and an AB hydrolase fold, and is classified as an apoplastic effector. The gene is associated with proteolysis, zymogen activation, protein catabolism in the vacuole, secretion, and monocarboxylic acid and antibiotic anabolism. It localises to the fungal-type vacuole, plasma membrane, and side of membrane. VdCP1 is associated with increased necrotic cell death, abnormal autophagy, altered protein secretion, increased aneuploidy, and decreased cytokinesis, as well as effects on lifespan, prion inheritance, and mitophagy.