BCR1 — Verticillium dahliae

Summary

VdBCR1 (VDAG_00586) on chromosome DS572695 of Verticillium dahliae encodes a C2H2 zinc-finger transcription factor of the CreA/MIG family, with DNA-binding and zinc-binding activity. The gene is associated with carbon catabolite repression, gluconeogenesis, regulation of gene expression, and the oxidative branch of the pentose pathway. It is linked to hyphal growth, chromatin modeling, and localization to both the cytoplasm and nucleus. VdBCR1 is associated with vascular wilt disease in cotton (Gossypium hirsutum). Phenotypic associations include altered sporulation, pseudohyphal growth, adhesion, UV and ionizing radiation resistance, nitrogen utilization, cell cycle progression, autophagy, chitin deposition, and mating-related processes. Studies of related genes in other species link the family to sugar content, germination rate, acid sensitivity, and oxidative stress response.