gef1 — Schizosaccharomyces pombe 972h-

Summary

SPAC24H6.09 (gef1) on chromosome 1 of Schizosaccharomyces pombe encodes a protein containing a Dynamin-Rho_GEF domain and a DH domain, and is annotated with the molecular function GDS. The gene is associated with regulation of protein localization to cell division site involved in cell separation after cytokinesis, positive regulation of septum digestion after cytokinesis, regulation of actomyosin contractile ring contraction, regulation of division septum assembly, downregulation of endocytosis, exocyst localization, cell polarization, cell morphogenesis, polar cell growth, and the DNA replication checkpoint. The product localizes to the endocytic patch, medial cortex septin ring, cell cortex of growing cell tip, mitotic actomyosin contractile ring, division septum, and cell division site.