MIH1 — Schizosaccharomyces pombe 972h-

Summary

MIH1 (SPAC24H6.05) in Schizosaccharomyces pombe 972h- encodes a protein tyrosine phosphatase (EC 3.1.3.48) belonging to the MPI_Phosphatase family, with a rhodanese-like domain. The gene is associated with a wide range of biological processes, including plant organ formation, root morphogenesis and development, shoot development, response to ethylene, and ethylene anabolism. It is also linked to cell cycle regulation, specifically negative regulation of the cell cycle, positive regulation of the G2/M transition of the meiotic cell cycle, and both upregulation and downregulation of mitosis. Additional associations include cell tip growth, embryogenesis, gastrulation, response to hydrostatic pressure and caffeine, S-nitrosylation, and siRNA-mediated PTGS. The encoded protein localises to the cytoplasm, cytosol, and nucleus. Trait associations include root width, cell membrane stability, leaf shape, and protein content. Related genes in other species are linked to M-phase inducer phosphatase.

Annotations

Chromosome
1
Related genes
MIH1
GO terms
Localization, embryogenesis, Cell Cycle, Cellular Homeostasis, cell physiology, Gastrulation, siRNA-mediated PTGS, Response To Caffeine
Publications
PMID:1334559, PMID:24835271, PMID:15659171, PMID:10628841, PMID:7796803, PMID:2649252, PMID:26715668, PMID:11085271
Traits
protein content, cell membrane stability, leaf shape, root width