MEDA — Neurospora crassa

Summary

NCU07617 (MEDA, NcMEDA) on Neurospora crassa chromosome 4 encodes the Acr1 protein, which contains the DUF7082 domain. The gene is associated with circadian rhythm, conidiophore development, sporulation, and morphogenesis, and has been linked to hypersensitivity and membrane transport. Its product localises to the nucleus. MEDA is also associated with iron concentration and oxidative stress response. Studies of related genes in other species link the family to RNaseH_sf domain-containing proteins, though these associations are not established for NcMEDA itself.