ZC246 — Neurospora crassa

Summary

NCU07788 (symbol ZC246, also known as col-26) on Neurospora crassa chromosome 5 encodes a Zn2Cys6 DNA-binding domain transcription factor with RNA polymerase II-specific transcription factor activity, DNA binding, and zinc binding functions. The protein localises to the nucleus. This gene is associated with carbon catabolite repression, the glucose effect, and catabolite repression, as well as the GABA shunt, starch and maltose breakdown, the TCA cycle, and secretion. It has also been connected to positive regulation of cell-substrate adhesion, upregulation of cell adhesion involved in single-species biofilm formation, and biofilm formation on inanimate substrates. Related genes in other species, including Fusarium and Verticillium, encode C6 zinc finger proteins.