smtA — Neurospora crassa

Summary

NCU05216 (smtA) on Neurospora crassa chromosome 4 encodes a methoxy mycolic acid synthase 1, a member of the CFA/CMAS and SAM-dependent methyltransferase superfamilies, with methyltransferase activity. The gene is associated with glucosylceramide anabolism, sphingolipid metabolism, methylation, regulation of gene expression, filamentous growth, mating, sexual reproduction, and fruiting body formation. Its product localises to the plasma membrane, membrane, and extracellular vesicles. Related genes in other species are linked to cyclopropane-fatty-acyl-phospholipid synthase and EC 2.1.1.317, and are associated with reduced virulence and fusarium head blight.