CHSD — Neurospora crassa

Summary

NCU05268 (CHSD, chs-6) in Neurospora crassa chromosome 4 encodes a chitin synthase with chitin synthase activity (EC 2.4.1.16) and also exhibits cytoskeletal motor activity, actin binding, and ATP binding. The protein localizes to the apical plasma membrane, chitosome, myosin complex, cross wall, incipient cellular bud site, cellular bud neck, and cell tip. CHSD is associated with chitin anabolism, cell wall organization, fungal-type cell wall organization, hyphal growth, asexual sporulation, ascospore wall assembly, ascospore formation, and protein localization to the bud neck. Related genes in other species are linked to polysaccharide content and reduced virulence, though these associations are not established for N. crassa.