GANB — Neurospora crassa

Summary

NCU05206 (GANB, gna-3) on Neurospora crassa chromosome 4 encodes a G-protein alpha subunit (Gprotein_alpha_su family) with GTPase activity, GTP binding, and adenylate cyclase activator activity. It is associated with the heterotrimeric G-protein complex and cytoplasm, and is linked to GPCR signaling, cAMP metabolism, the glucose-sensing PKA pathway, and adenylate cyclase-activating GPCR signaling. The gene has been connected to asexual sporulation, conidia formation, sexual reproduction, ascospore formation, pseudohyphal growth, hyphal growth, invasive growth in response to glucose limitation, pheromone response, and cellulose breakdown. Related genes in other species are linked to germination rate and virulence phenotypes including reduced virulence.